High diversity of Escherichia coli causing invasive disease in neonates in Malawi poses challenges for O-antigen based vaccine approach
Abstract Background Escherichia coli is an important cause of neonatal sepsis and the third most prevalent cause of neonatal infection in sub-Saharan Africa, often with negative outcomes. Development of maternally administered vaccines is under consideration, but to provide adequate protection, an u...
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| Main Authors: | Oliver Pearse, Allan Zuza, Edith Tewesa, Patricia Siyabu, Alice J. Fraser, Jennifer Cornick, Kondwani Kawaza, Patrick Musicha, Nicholas R. Thomson, Nicholas A. Feasey, Eva Heinz |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Nature Portfolio
2025-07-01
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| Series: | Communications Medicine |
| Online Access: | https://doi.org/10.1038/s43856-025-01007-1 |
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