High glucose reduces Nrf2-dependent cRAGE release and enhances inflammasome-dependent IL-1β production in monocytes: the modulatory effects of EGCG
Soluble receptor for advanced glycation end products (sRAGE) acts as a decoy sequestering of RAGE ligands, thus preventing the activation of the ligand-RAGE axis linking human diseases. However, the molecular mechanisms underlying sRAGE remain unclear. In this study, THP-1 monocytes were cultured in...
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Main Authors: | , , , , |
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Format: | Article |
Language: | English |
Published: |
Tsinghua University Press
2024-05-01
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Series: | Food Science and Human Wellness |
Subjects: | |
Online Access: | https://www.sciopen.com/article/10.26599/FSHW.2022.9250129 |
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