TRIM8 inhibits porcine epidemic diarrhoea virus replication by targeting and ubiquitinately degrading the nucleocapsid protein
Abstract Porcine epidemic diarrhoea virus (PEDV) is an enteric pathogen that causes acute diarrhoea, dehydration and high mortality rates in suckling pigs. Tripartite motif 8 (TRIM8) has been shown to play multiple roles in the host’s defence against viral infections. However, the functions of TRIM8...
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Main Authors: | Zhenbin Bi, Wei Wang, Shanshen Gu, Yajing Zhou, Zhengchang Wu, Wenbin Bao, Haifei Wang |
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Format: | Article |
Language: | English |
Published: |
BMC
2025-01-01
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Series: | Veterinary Research |
Subjects: | |
Online Access: | https://doi.org/10.1186/s13567-024-01443-2 |
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