TRIM8 inhibits porcine epidemic diarrhoea virus replication by targeting and ubiquitinately degrading the nucleocapsid protein

TRIM8 inhibits porcine epidemic diarrhoea virus replication by targeting and ubiquitinately degrading the nucleocapsid protein

Abstract Porcine epidemic diarrhoea virus (PEDV) is an enteric pathogen that causes acute diarrhoea, dehydration and high mortality rates in suckling pigs. Tripartite motif 8 (TRIM8) has been shown to play multiple roles in the host’s defence against viral infections. However, the functions of TRIM8...

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Bibliographic Details
Main Authors: Zhenbin Bi, Wei Wang, Shanshen Gu, Yajing Zhou, Zhengchang Wu, Wenbin Bao, Haifei Wang
Format: Article
Language:English
Published: BMC 2025-01-01
Series:Veterinary Research
Subjects:
PED
virus-host protein interaction
virus infection
ubiquitination
antiviral response
Online Access:https://doi.org/10.1186/s13567-024-01443-2
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https://doi.org/10.1186/s13567-024-01443-2

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