Identification of determinants that allow maintenance of high-level fluoroquinolone resistance in Acinetobacter baumannii
ABSTRACT Acinetobacter baumannii is associated with multidrug-resistant infections in healthcare settings, with fluoroquinolones such as ciprofloxacin being currently ineffective. Clinical isolates largely harbor mutations in the GyrA and TopoIV fluoroquinolone targets, as well as mutations that inc...
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Main Authors: | , , , , , , , , , |
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Format: | Article |
Language: | English |
Published: |
American Society for Microbiology
2025-01-01
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Series: | mBio |
Subjects: | |
Online Access: | https://journals.asm.org/doi/10.1128/mbio.03221-24 |
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