SHP2 promotes the epithelial-mesenchymal transition in triple negative breast cancer cells by regulating β-catenin
Abstract Purpose Growing evidence suggests that the tyrosine phosphatase SHP2 is pivotal for tumor progression. Triple-negative breast cancer (TNBC) is the most lethal subtype of breast cancer, characterized by its high recurrence rate, aggressive metastasis, and resistance to chemotherapy. Understa...
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Main Authors: | Shihan Qian, Jingjing Zhu, Qing Han, Huang Cheng, Huaibin Zhou |
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Format: | Article |
Language: | English |
Published: |
Springer
2025-01-01
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Series: | Journal of Cancer Research and Clinical Oncology |
Subjects: | |
Online Access: | https://doi.org/10.1007/s00432-025-06097-x |
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