Motif distribution and DNA methylation underlie distinct Cdx2 binding during development and homeostasis
Abstract Transcription factors guide tissue development by binding to developmental stage-specific targets and establishing an appropriate enhancer landscape. In turn, DNA and chromatin modifications direct the genomic binding of transcription factors. However, how transcription factors navigate chr...
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Main Authors: | Alireza Lorzadeh, George Ye, Sweta Sharma, Unmesh Jadhav |
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Format: | Article |
Language: | English |
Published: |
Nature Portfolio
2025-01-01
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Series: | Nature Communications |
Online Access: | https://doi.org/10.1038/s41467-025-56187-0 |
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