Motif distribution and DNA methylation underlie distinct Cdx2 binding during development and homeostasis

Abstract Transcription factors guide tissue development by binding to developmental stage-specific targets and establishing an appropriate enhancer landscape. In turn, DNA and chromatin modifications direct the genomic binding of transcription factors. However, how transcription factors navigate chr...

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Bibliographic Details
Main Authors: Alireza Lorzadeh, George Ye, Sweta Sharma, Unmesh Jadhav
Format: Article
Language:English
Published: Nature Portfolio 2025-01-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-025-56187-0
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