Evolutionary processes acting on candidate cis-regulatory regions in humans inferred from patterns of polymorphism and divergence.
Analysis of polymorphism and divergence in the non-coding portion of the human genome yields crucial information about factors driving the evolution of gene regulation. Candidate cis-regulatory regions spanning more than 15,000 genes in 15 African Americans and 20 European Americans were re-sequence...
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| Main Authors: | Dara G Torgerson, Adam R Boyko, Ryan D Hernandez, Amit Indap, Xiaolan Hu, Thomas J White, John J Sninsky, Michele Cargill, Mark D Adams, Carlos D Bustamante, Andrew G Clark |
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| Format: | Article |
| Language: | English |
| Published: |
Public Library of Science (PLoS)
2009-08-01
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| Series: | PLoS Genetics |
| Online Access: | https://journals.plos.org/plosgenetics/article/file?id=10.1371/journal.pgen.1000592&type=printable |
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