Evolutionary processes acting on candidate cis-regulatory regions in humans inferred from patterns of polymorphism and divergence.

Evolutionary processes acting on candidate cis-regulatory regions in humans inferred from patterns of polymorphism and divergence.

Analysis of polymorphism and divergence in the non-coding portion of the human genome yields crucial information about factors driving the evolution of gene regulation. Candidate cis-regulatory regions spanning more than 15,000 genes in 15 African Americans and 20 European Americans were re-sequence...

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Bibliographic Details
Main Authors: Dara G Torgerson, Adam R Boyko, Ryan D Hernandez, Amit Indap, Xiaolan Hu, Thomas J White, John J Sninsky, Michele Cargill, Mark D Adams, Carlos D Bustamante, Andrew G Clark
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2009-08-01
Series:PLoS Genetics
Online Access:https://journals.plos.org/plosgenetics/article/file?id=10.1371/journal.pgen.1000592&type=printable
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https://journals.plos.org/plosgenetics/article/file?id=10.1371/journal.pgen.1000592&type=printable

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