Loss of neuronal βPix isoforms impairs neuronal morphology in the hippocampus and causes behavioral defects
βPix is a guanine nucleotide exchange factor for the Rac1 and Cdc42 small GTPases, which play important roles in dendritic spine morphogenesis by modulating actin cytoskeleton organization. The formation and plasticity of the dendritic spines are essential for normal brain function. Among the altern...
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Main Authors: | , , , , , |
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Format: | Article |
Language: | English |
Published: |
Taylor & Francis Group
2025-12-01
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Series: | Animal Cells and Systems |
Subjects: | |
Online Access: | https://www.tandfonline.com/doi/10.1080/19768354.2024.2448999 |
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