Loss of neuronal βPix isoforms impairs neuronal morphology in the hippocampus and causes behavioral defects

βPix is a guanine nucleotide exchange factor for the Rac1 and Cdc42 small GTPases, which play important roles in dendritic spine morphogenesis by modulating actin cytoskeleton organization. The formation and plasticity of the dendritic spines are essential for normal brain function. Among the altern...

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Bibliographic Details
Main Authors: Younghee Kwon, Seung Joon Lee, Yoon Kyung Shin, June-Seek Choi, Dongeun Park, Jung Eun Shin
Format: Article
Language:English
Published: Taylor & Francis Group 2025-12-01
Series:Animal Cells and Systems
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Online Access:https://www.tandfonline.com/doi/10.1080/19768354.2024.2448999
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