Rapid high yield production of different glycoforms of Ebola virus monoclonal antibody.
<h4>Background</h4>Fc-glycosylation of monoclonal antibodies (mAbs) has profound implications on the Fc-mediated effector functions. Alteration of this glycosylation may affect the efficiency of an antibody. However, difficulties in the production of mAbs with homogeneous N-glycosylation...
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| Main Authors: | Alexandra Castilho, Natasha Bohorova, Josephine Grass, Ognian Bohorov, Larry Zeitlin, Kevin Whaley, Friedrich Altmann, Herta Steinkellner |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Public Library of Science (PLoS)
2011-01-01
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| Series: | PLoS ONE |
| Online Access: | https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0026040&type=printable |
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