Rapid high yield production of different glycoforms of Ebola virus monoclonal antibody.

<h4>Background</h4>Fc-glycosylation of monoclonal antibodies (mAbs) has profound implications on the Fc-mediated effector functions. Alteration of this glycosylation may affect the efficiency of an antibody. However, difficulties in the production of mAbs with homogeneous N-glycosylation...

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Bibliographic Details
Main Authors: Alexandra Castilho, Natasha Bohorova, Josephine Grass, Ognian Bohorov, Larry Zeitlin, Kevin Whaley, Friedrich Altmann, Herta Steinkellner
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0026040&type=printable
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