Aging disrupts the link between network centrality and functional properties of prefrontal neurons during memory-guided behavior
Abstract The prefrontal cortex (PFC) is vital for higher cognitive functions and displays neuronal heterogeneity, with neuronal activity varying significantly across individual neurons. Using calcium imaging in the medial PFC (mPFC) of mice, we investigate whether differences in degree centrality—a...
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Main Authors: | Yadollah Ranjbar-Slamloo, Huee Ru Chong, Tsukasa Kamigaki |
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Format: | Article |
Language: | English |
Published: |
Nature Portfolio
2025-01-01
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Series: | Communications Biology |
Online Access: | https://doi.org/10.1038/s42003-025-07498-x |
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