Aging disrupts the link between network centrality and functional properties of prefrontal neurons during memory-guided behavior

Abstract The prefrontal cortex (PFC) is vital for higher cognitive functions and displays neuronal heterogeneity, with neuronal activity varying significantly across individual neurons. Using calcium imaging in the medial PFC (mPFC) of mice, we investigate whether differences in degree centrality—a...

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Bibliographic Details
Main Authors: Yadollah Ranjbar-Slamloo, Huee Ru Chong, Tsukasa Kamigaki
Format: Article
Language:English
Published: Nature Portfolio 2025-01-01
Series:Communications Biology
Online Access:https://doi.org/10.1038/s42003-025-07498-x
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