The role of protein lactylation in brain health and disease: current advances and future directions
Abstract Lactate, the end product of glycolysis, plays a crucial role in cellular signaling and metabolism. The discovery of lactylation, a novel post-translational modification, has uncovered the role of lactate in regulating diseases, especially in the brain. Lactylation connects genetic encoding...
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| Main Authors: | Mingrui Han, Wenfeng He, Wengen Zhu, Linjuan Guo |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Nature Publishing Group
2025-04-01
|
| Series: | Cell Death Discovery |
| Online Access: | https://doi.org/10.1038/s41420-025-02408-w |
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