OGT-mediated O-GlcNAcylation regulates macrophage polarization in heart failure via targeting IRF1

Abstract Background Heart failure (HF) is a syndrome with complex etiology and high mortality in the world. Macrophage-related inflammation is involved in HF development. O-GlcNAcylation is a post-translational modification that affects pathological processes. This study aimed to investigate the rol...

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Bibliographic Details
Main Authors: Guoqiang Jing, Yuhong Ma
Format: Article
Language:English
Published: BMC 2024-12-01
Series:BMC Cardiovascular Disorders
Subjects:
Online Access:https://doi.org/10.1186/s12872-024-04429-2
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