OGT-mediated O-GlcNAcylation regulates macrophage polarization in heart failure via targeting IRF1
Abstract Background Heart failure (HF) is a syndrome with complex etiology and high mortality in the world. Macrophage-related inflammation is involved in HF development. O-GlcNAcylation is a post-translational modification that affects pathological processes. This study aimed to investigate the rol...
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Main Authors: | , |
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Format: | Article |
Language: | English |
Published: |
BMC
2024-12-01
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Series: | BMC Cardiovascular Disorders |
Subjects: | |
Online Access: | https://doi.org/10.1186/s12872-024-04429-2 |
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