In vitro study of size-dependent inhibition of human cytochrome P450 (P450) P450-1A2, P450-2A6, P450-2B6, P450-2C8, P450-2E1, P450-2J2, and P450-3A5 by zinc oxide nanoparticles (ZnONPs)
Zinc oxide nanoparticles (ZnONPs) are employed widely in various fields. However, these ZnONPs may potentially inhibit enzyme activities. Cytochrome P450 (P450-) isozymes, which play a crucial function in human bio-transforming drugs, can be inhibited by ZnONPs, leading to slower clearance of co-adm...
Saved in:
Main Authors: | Lamia Chowdhury, Yuh Fen Pung, Swee Yong Pung, Chin Eng Ong, Cin Kong, Yan Pan |
---|---|
Format: | Article |
Language: | English |
Published: |
Andover House Inc.
2025-02-01
|
Series: | Precision Nanomedicine |
Online Access: | https://doi.org/10.33218/001c.129234 |
Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
Target Proteins in Human Autoimmunity: Cytochromes P450 and Udp-Glycoronosyltransferases
by: Petra Obermayer-Straub, et al.
Published: (2000-01-01) -
Physicochemical properties and cytochromes P-450 kinetics of the trifluoroacetamido derivative of phenacetin
by: Hannah L. Cure, et al.
Published: (2025-01-01) -
Screening of flavonoid aglycons’ metabolism mediated by the human liver cytochromes P450
by: Benković Goran, et al.
Published: (2019-12-01) -
Effects of Cytochrome P450 Inhibitors on Itraconazole and Fluconazole Induced Cytotoxicity in Hepatocytes
by: Nhareet Somchit, et al.
Published: (2009-01-01) -
Cardiovascular Side Effects of Atomoxetine and Its Interactions with Inhibitors of the Cytochrome P450 System
by: Pashtoon Murtaza Kasi, et al.
Published: (2011-01-01)