In vitro study of size-dependent inhibition of human cytochrome P450 (P450) P450-1A2, P450-2A6, P450-2B6, P450-2C8, P450-2E1, P450-2J2, and P450-3A5 by zinc oxide nanoparticles (ZnONPs)
Zinc oxide nanoparticles (ZnONPs) are employed widely in various fields. However, these ZnONPs may potentially inhibit enzyme activities. Cytochrome P450 (P450-) isozymes, which play a crucial function in human bio-transforming drugs, can be inhibited by ZnONPs, leading to slower clearance of co-adm...
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Main Authors: | , , , , , |
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Format: | Article |
Language: | English |
Published: |
Andover House Inc.
2025-02-01
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Series: | Precision Nanomedicine |
Online Access: | https://doi.org/10.33218/001c.129234 |
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