Causality between insulin use and malignant tumors of the digestive system: a two-sample mendelian randomized study

Abstract Background Existing cohort studies show no association between insulin use and cancers of the digestive system, while numerous meta-analyses suggest that insulin use increases the risk of digestive system tumours. This study uses two-sample Mendelian randomization (MR) to further investigat...

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Bibliographic Details
Main Authors: DengZhuo Chen, YongLi Ma, JingHui Li, Liang Wen, GuoSheng Zhang, ChengZhi Huang, XueQing Yao
Format: Article
Language:English
Published: BMC 2025-01-01
Series:BMC Cancer
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Online Access:https://doi.org/10.1186/s12885-025-13452-1
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