Two Cases of Sarcoma Arising in Giant Cell Tumor of Bone Treated with Denosumab
Giant cell tumor (GCT) of bone is a generally benign, but often locally aggressive, neoplasm of bone, with a propensity for recurrence. Sarcomatous transformation is rare and typically occurs with a history of recurrences and radiation treatment. Denosumab, an inhibitor of the RANK ligand involved i...
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Main Authors: | Cory Julian Broehm, Erika L. Garbrecht, Jeff Wood, Therese Bocklage |
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Format: | Article |
Language: | English |
Published: |
Wiley
2015-01-01
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Series: | Case Reports in Medicine |
Online Access: | http://dx.doi.org/10.1155/2015/767198 |
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