Two Cases of Sarcoma Arising in Giant Cell Tumor of Bone Treated with Denosumab

Giant cell tumor (GCT) of bone is a generally benign, but often locally aggressive, neoplasm of bone, with a propensity for recurrence. Sarcomatous transformation is rare and typically occurs with a history of recurrences and radiation treatment. Denosumab, an inhibitor of the RANK ligand involved i...

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Bibliographic Details
Main Authors: Cory Julian Broehm, Erika L. Garbrecht, Jeff Wood, Therese Bocklage
Format: Article
Language:English
Published: Wiley 2015-01-01
Series:Case Reports in Medicine
Online Access:http://dx.doi.org/10.1155/2015/767198
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