Immune Response in Severe Infection: Could Life-Saving Drugs Be Potentially Harmful?

Critically ill patients suffer a high rate of nosocomial infection with secondary sepsis being a common cause of death. Usage of antibiotics and catecholamines is often necessary, but it can compromise complex immune response to infection. This review explores influence of these life-saving drugs on...

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Main Authors: Maja Surbatovic, Jasna Jevdjic, Milic Veljovic, Nada Popovic, Dragan Djordjevic, Sonja Radakovic
Format: Article
Language:English
Published: Wiley 2013-01-01
Series:The Scientific World Journal
Online Access:http://dx.doi.org/10.1155/2013/961852
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author Maja Surbatovic
Jasna Jevdjic
Milic Veljovic
Nada Popovic
Dragan Djordjevic
Sonja Radakovic
author_facet Maja Surbatovic
Jasna Jevdjic
Milic Veljovic
Nada Popovic
Dragan Djordjevic
Sonja Radakovic
author_sort Maja Surbatovic
collection DOAJ
description Critically ill patients suffer a high rate of nosocomial infection with secondary sepsis being a common cause of death. Usage of antibiotics and catecholamines is often necessary, but it can compromise complex immune response to infection. This review explores influence of these life-saving drugs on host immune response to severe infection.
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institution Kabale University
issn 1537-744X
language English
publishDate 2013-01-01
publisher Wiley
record_format Article
series The Scientific World Journal
spelling doaj-art-ffcdb442445e4895b5bba51b8f2ad61a2025-02-03T01:30:10ZengWileyThe Scientific World Journal1537-744X2013-01-01201310.1155/2013/961852961852Immune Response in Severe Infection: Could Life-Saving Drugs Be Potentially Harmful?Maja Surbatovic0Jasna Jevdjic1Milic Veljovic2Nada Popovic3Dragan Djordjevic4Sonja Radakovic5Clinic of Anesthesiology and Intensive Therapy, Military Medical Academy, Crnotravska 17, 11000 Belgrade, SerbiaClinical Center Kragujevac, Zmaj Jovina 30, 34000 Kragujevac, SerbiaClinic of Anesthesiology and Intensive Therapy, Military Medical Academy, Crnotravska 17, 11000 Belgrade, SerbiaInstitute for Infectious and Tropical Diseases, Intensive Care Unit, Clinical Center of Serbia, Pasterova 2, 11000 Belgrade, SerbiaClinic of Anesthesiology and Intensive Therapy, Military Medical Academy, Crnotravska 17, 11000 Belgrade, SerbiaFaculty of Medicine of the Military Medical Academy, University of Defense, Crnotravska 17, 11000 Belgrade, SerbiaCritically ill patients suffer a high rate of nosocomial infection with secondary sepsis being a common cause of death. Usage of antibiotics and catecholamines is often necessary, but it can compromise complex immune response to infection. This review explores influence of these life-saving drugs on host immune response to severe infection.http://dx.doi.org/10.1155/2013/961852
spellingShingle Maja Surbatovic
Jasna Jevdjic
Milic Veljovic
Nada Popovic
Dragan Djordjevic
Sonja Radakovic
Immune Response in Severe Infection: Could Life-Saving Drugs Be Potentially Harmful?
The Scientific World Journal
title Immune Response in Severe Infection: Could Life-Saving Drugs Be Potentially Harmful?
title_full Immune Response in Severe Infection: Could Life-Saving Drugs Be Potentially Harmful?
title_fullStr Immune Response in Severe Infection: Could Life-Saving Drugs Be Potentially Harmful?
title_full_unstemmed Immune Response in Severe Infection: Could Life-Saving Drugs Be Potentially Harmful?
title_short Immune Response in Severe Infection: Could Life-Saving Drugs Be Potentially Harmful?
title_sort immune response in severe infection could life saving drugs be potentially harmful
url http://dx.doi.org/10.1155/2013/961852
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