Clinical evaluation of platelet rich fibrin as barrier membrane in treatment of grade II furcation defects

Background and Objectives: Various guided tissue regenerative procedures have been used in treatment of furcation defects. A combination of various graft materials and barrier membranes have been used over a period of time. The present study was designed to test whether autologous platelet-rich fibr...

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Main Authors: B. Harshavardhana, Nitin Gupta, Spandana Reddy Vantary, Ankit Krishna
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2024-07-01
Series:Journal of Indian Society of Periodontology
Subjects:
Online Access:https://journals.lww.com/10.4103/jisp.jisp_6_24
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author B. Harshavardhana
Nitin Gupta
Spandana Reddy Vantary
Ankit Krishna
author_facet B. Harshavardhana
Nitin Gupta
Spandana Reddy Vantary
Ankit Krishna
author_sort B. Harshavardhana
collection DOAJ
description Background and Objectives: Various guided tissue regenerative procedures have been used in treatment of furcation defects. A combination of various graft materials and barrier membranes have been used over a period of time. The present study was designed to test whether autologous platelet-rich fibrin (PRF) can be effectively used as a barrier membrane along with porous hydroxyapatite (HA) bone graft in the treatment of Grade II furcation defects. Materials and Methods: The present study was a split-mouth design, in which a total of thirty patients with bilateral grade II furcation defects in the mandibular molars were selected. On the control side, the furcation defect was treated using only HA bone graft and in the test side, the furcation defect was treated using a combination of HA bone graft and PRF as barrier membrane. The clinical and radiological parameters were recorded presurgically, postsurgical at 3 and 6 months, respectively, and the results were statistically analyzed and compared. Results: The furcation defects treated in the test side showed better healing and bone fill when compared to control side. The clinical parameters of the test and control sides when compared were found to be statistically significant. Conclusion: PRF can be effectively used as barrier membrane along with a graft material thus enhancing the regenerative potential of the graft material while regenerating the lost periodontal tissue in Grade II furcation defects.
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institution Kabale University
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0975-1580
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publisher Wolters Kluwer Medknow Publications
record_format Article
series Journal of Indian Society of Periodontology
spelling doaj-art-ffc2587cfa4b4cbf8f3469a07e7e67242025-02-06T07:19:22ZengWolters Kluwer Medknow PublicationsJournal of Indian Society of Periodontology0972-124X0975-15802024-07-0128443143510.4103/jisp.jisp_6_24Clinical evaluation of platelet rich fibrin as barrier membrane in treatment of grade II furcation defectsB. HarshavardhanaNitin GuptaSpandana Reddy VantaryAnkit KrishnaBackground and Objectives: Various guided tissue regenerative procedures have been used in treatment of furcation defects. A combination of various graft materials and barrier membranes have been used over a period of time. The present study was designed to test whether autologous platelet-rich fibrin (PRF) can be effectively used as a barrier membrane along with porous hydroxyapatite (HA) bone graft in the treatment of Grade II furcation defects. Materials and Methods: The present study was a split-mouth design, in which a total of thirty patients with bilateral grade II furcation defects in the mandibular molars were selected. On the control side, the furcation defect was treated using only HA bone graft and in the test side, the furcation defect was treated using a combination of HA bone graft and PRF as barrier membrane. The clinical and radiological parameters were recorded presurgically, postsurgical at 3 and 6 months, respectively, and the results were statistically analyzed and compared. Results: The furcation defects treated in the test side showed better healing and bone fill when compared to control side. The clinical parameters of the test and control sides when compared were found to be statistically significant. Conclusion: PRF can be effectively used as barrier membrane along with a graft material thus enhancing the regenerative potential of the graft material while regenerating the lost periodontal tissue in Grade II furcation defects.https://journals.lww.com/10.4103/jisp.jisp_6_24barrier membranefurcation defectsguided tissue regenerationplatelet-rich fibrin
spellingShingle B. Harshavardhana
Nitin Gupta
Spandana Reddy Vantary
Ankit Krishna
Clinical evaluation of platelet rich fibrin as barrier membrane in treatment of grade II furcation defects
Journal of Indian Society of Periodontology
barrier membrane
furcation defects
guided tissue regeneration
platelet-rich fibrin
title Clinical evaluation of platelet rich fibrin as barrier membrane in treatment of grade II furcation defects
title_full Clinical evaluation of platelet rich fibrin as barrier membrane in treatment of grade II furcation defects
title_fullStr Clinical evaluation of platelet rich fibrin as barrier membrane in treatment of grade II furcation defects
title_full_unstemmed Clinical evaluation of platelet rich fibrin as barrier membrane in treatment of grade II furcation defects
title_short Clinical evaluation of platelet rich fibrin as barrier membrane in treatment of grade II furcation defects
title_sort clinical evaluation of platelet rich fibrin as barrier membrane in treatment of grade ii furcation defects
topic barrier membrane
furcation defects
guided tissue regeneration
platelet-rich fibrin
url https://journals.lww.com/10.4103/jisp.jisp_6_24
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AT spandanareddyvantary clinicalevaluationofplateletrichfibrinasbarriermembraneintreatmentofgradeiifurcationdefects
AT ankitkrishna clinicalevaluationofplateletrichfibrinasbarriermembraneintreatmentofgradeiifurcationdefects