Protective effect and mechanism of Xiaoyu Xiezhuo decoction on ischemia–reperfusion induced acute kidney injury based on gut–kidney crosstalk

Protective effect and mechanism of Xiaoyu Xiezhuo decoction on ischemia–reperfusion induced acute kidney injury based on gut–kidney crosstalk

This study aimed to explore the mechanism of Xiaoyu Xiezhuo decoction (XXD) on ischemia–reperfusion-induced acute kidney injury (IRI-AKI) using network pharmacology methods and gut microbiota analysis. A total of 1778 AKI-related targets were obtained, including 140 targets possibly regulated by AKI...

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Bibliographic Details
Main Authors: Yue Ji, Yunming Xiao, Shipian Li, Yihua Fan, Yuzi Cai, Bo Yang, Hongbo Chen, Shouci Hu
Format: Article
Language:English
Published: Taylor & Francis Group 2024-12-01
Series:Renal Failure
Subjects:
Xiaoyu Xiezhuo decoction
network pharmacology
acute kidney injury
gut flora
Online Access:https://www.tandfonline.com/doi/10.1080/0886022X.2024.2365982
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