CircMYH9/miR-133a-3p/CXCR4 axis: a novel regulatory network in sperm fertilization and embryo development

CircMYH9/miR-133a-3p/CXCR4 axis: a novel regulatory network in sperm fertilization and embryo development

Abstract This study aimed to investigate the influence of sperm miRNAs on fertilization rates (FR) in in vitro fertilization (IVF) and to explore potential regulatory mechanisms in sperm-mediated fertilization and embryo development. Through high-throughput sequencing, we identified differentially e...

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Bibliographic Details
Main Authors: Qian Sun, Yanyu Li, Wen Yang, Wen Feng, Jiayun Zhou, Yijuan Cao, Bei Zhang, Zuobin Zhu, Conghui Han
Format: Article
Language:English
Published: Springer 2024-12-01
Series:Molecular Biomedicine
Subjects:
Sperm
CircMYH9
miR-133a-3p
CXCR4
In vitro fertilization rate
Embryo development
Online Access:https://doi.org/10.1186/s43556-024-00236-5
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