BRCA cascade counselling and testing in Italy: current position and future directions

BRCA cascade counselling and testing in Italy: current position and future directions

Abstract Background Genetic testing has led to a considerable enhancement in the ability to identify individuals at risk of Hereditary Breast and Ovarian Cancer syndrome related to BRCA1/2 pathogenic variants, thus necessitating personalised prevention programs. However, barriers related to intrafam...

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Main Authors: Silvia Costanzo, Lea Godino, Simona De Summa, Tommaso Maria Marvulli, Maurizio Genuardi, Maria Luisa Di Pietro, Emanuela Lucci Cordisco, Daniela Turchetti, Sara Miccoli, Giuseppe Deledda, Giovanna Fantoni, Valeria Viassolo, Oronzo Brunetti, Raffaele De Luca, Maria Digennaro, Francesca Romito, Maria Campanella, Margherita Patruno
Format: Article
Language:English
Published: BMC 2025-07-01
Series:BMC Cancer
Subjects:
BRCA1/2
Cascade genetic counselling and testing
Communication
Mainstream cancer genetics
Psychological distress
Traditional genetic counselling
Online Access:https://doi.org/10.1186/s12885-025-14419-y
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