HLA class I binding of HBZ determines outcome in HTLV-1 infection.

CD8(+) T cells can exert both protective and harmful effects on the virus-infected host. However, there is no systematic method to identify the attributes of a protective CD8(+) T cell response. Here, we combine theory and experiment to identify and quantify the contribution of all HLA class I allel...

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Bibliographic Details
Main Authors: Aidan Macnamara, Aileen Rowan, Silva Hilburn, Ulrich Kadolsky, Hiroshi Fujiwara, Koichiro Suemori, Masaki Yasukawa, Graham Taylor, Charles R M Bangham, Becca Asquith
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-09-01
Series:PLoS Pathogens
Online Access:https://journals.plos.org/plospathogens/article/file?id=10.1371/journal.ppat.1001117&type=printable
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