Group IIC self-splicing intron-derived novel circular RNA vaccine elicits superior immune response against RSV

Group IIC self-splicing intron-derived novel circular RNA vaccine elicits superior immune response against RSV

IntroductionThe remarkable commercial success of mRNA vaccines against COVID-19 and tumors, along with their potential as therapeutic drugs, has significantly boosted enthusiasm for circular RNAs (circRNA) as a promising next-generation therapeutic platform. The development of novel circRNA cyclizat...

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Bibliographic Details
Main Authors: Zeyun Sun, Lirong Lu, Lijie Liu, Ruoxu Liang, Qiqi Zhang, Zhining Liu, Jiahao An, Qian Liu, Qingxin Wu, Shuai Wei, Long Zhang, Wei Peng
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-04-01
Series:Frontiers in Immunology
Subjects:
circular RNA
group IIC self-splicing intron
RSV
nucleic acid vaccine
PIE
immune response
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2025.1574568/full
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https://www.frontiersin.org/articles/10.3389/fimmu.2025.1574568/full

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