Endourologic Management of Upper Tract Transitional Cell Carcinoma following Cystectomy and Urinary Diversion

Traditionally, nephroureterectomy is the gold standard therapy for upper tract recurrence of transitional cell carcinoma (TCC) following cystectomy and urinary diversion. With advances in endoscopic equipment and improvements in technique, conservative endourologic management via a retrograde or ant...

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Main Authors: Jeffrey John Tomaszewski, Marc Christopher Smaldone, Michael Cecil Ost
Format: Article
Language:English
Published: Wiley 2009-01-01
Series:Advances in Urology
Online Access:http://dx.doi.org/10.1155/2009/976401
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author Jeffrey John Tomaszewski
Marc Christopher Smaldone
Michael Cecil Ost
author_facet Jeffrey John Tomaszewski
Marc Christopher Smaldone
Michael Cecil Ost
author_sort Jeffrey John Tomaszewski
collection DOAJ
description Traditionally, nephroureterectomy is the gold standard therapy for upper tract recurrence of transitional cell carcinoma (TCC) following cystectomy and urinary diversion. With advances in endoscopic equipment and improvements in technique, conservative endourologic management via a retrograde or antegrade approach is technically feasible with acceptable outcomes in patients with bilateral disease, solitary renal units, chronic renal insufficiency, or significant medical comorbidities. Contemporary studies have expanded the utility of these techniques to include low-grade, low-volume disease in patients with a normal contralateral kidney. The aim of this report is to review the current outcomes of conservative management for upper tract disease and discuss its application and relevance in patients following cystectomy with lower urinary tract reconstruction.
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spelling doaj-art-feae971f89d04b54823fe7b50a90ea532025-02-03T01:28:49ZengWileyAdvances in Urology1687-63691687-63772009-01-01200910.1155/2009/976401976401Endourologic Management of Upper Tract Transitional Cell Carcinoma following Cystectomy and Urinary DiversionJeffrey John Tomaszewski0Marc Christopher Smaldone1Michael Cecil Ost2Department of Urology, University of Pittsburgh School of Medicine, Pittsburgh, PA 15213, USADepartment of Urology, University of Pittsburgh School of Medicine, Pittsburgh, PA 15213, USADepartment of Urology, University of Pittsburgh School of Medicine, Pittsburgh, PA 15213, USATraditionally, nephroureterectomy is the gold standard therapy for upper tract recurrence of transitional cell carcinoma (TCC) following cystectomy and urinary diversion. With advances in endoscopic equipment and improvements in technique, conservative endourologic management via a retrograde or antegrade approach is technically feasible with acceptable outcomes in patients with bilateral disease, solitary renal units, chronic renal insufficiency, or significant medical comorbidities. Contemporary studies have expanded the utility of these techniques to include low-grade, low-volume disease in patients with a normal contralateral kidney. The aim of this report is to review the current outcomes of conservative management for upper tract disease and discuss its application and relevance in patients following cystectomy with lower urinary tract reconstruction.http://dx.doi.org/10.1155/2009/976401
spellingShingle Jeffrey John Tomaszewski
Marc Christopher Smaldone
Michael Cecil Ost
Endourologic Management of Upper Tract Transitional Cell Carcinoma following Cystectomy and Urinary Diversion
Advances in Urology
title Endourologic Management of Upper Tract Transitional Cell Carcinoma following Cystectomy and Urinary Diversion
title_full Endourologic Management of Upper Tract Transitional Cell Carcinoma following Cystectomy and Urinary Diversion
title_fullStr Endourologic Management of Upper Tract Transitional Cell Carcinoma following Cystectomy and Urinary Diversion
title_full_unstemmed Endourologic Management of Upper Tract Transitional Cell Carcinoma following Cystectomy and Urinary Diversion
title_short Endourologic Management of Upper Tract Transitional Cell Carcinoma following Cystectomy and Urinary Diversion
title_sort endourologic management of upper tract transitional cell carcinoma following cystectomy and urinary diversion
url http://dx.doi.org/10.1155/2009/976401
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AT marcchristophersmaldone endourologicmanagementofuppertracttransitionalcellcarcinomafollowingcystectomyandurinarydiversion
AT michaelcecilost endourologicmanagementofuppertracttransitionalcellcarcinomafollowingcystectomyandurinarydiversion