The Central Roles of Noncoding RNA in Estrogen-Dependent Female Reproductive System Tumors
The pathogenesis of ovarian and endometrial cancers is closely associated with estrogen-related pathways. These estrogen-dependent tumors seriously threaten the health and quality of life in women. Noncoding RNAs (ncRNAs) are defined as RNAs that do not encode proteins, including microRNAs (miRNAs)...
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| Main Authors: | , , , , , , , , , |
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| Format: | Article |
| Language: | English |
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Wiley
2021-01-01
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| Series: | International Journal of Endocrinology |
| Online Access: | http://dx.doi.org/10.1155/2021/5572063 |
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| author | Jiajie Tu Huan Yang Lei Jiang Yu Chen Yu Chen Zhe Li Lei Li Yuanyuan Zhang Xiaochun Chen He Chen Zhiying Yu |
| author_facet | Jiajie Tu Huan Yang Lei Jiang Yu Chen Yu Chen Zhe Li Lei Li Yuanyuan Zhang Xiaochun Chen He Chen Zhiying Yu |
| author_sort | Jiajie Tu |
| collection | DOAJ |
| description | The pathogenesis of ovarian and endometrial cancers is closely associated with estrogen-related pathways. These estrogen-dependent tumors seriously threaten the health and quality of life in women. Noncoding RNAs (ncRNAs) are defined as RNAs that do not encode proteins, including microRNAs (miRNAs) and long noncoding RNAs (lncRNAs), both of which have been reported in estrogen-dependent female reproductive system tumors. This review systematically summarizes the role of ncRNAs in estrogen-dependent tumors and common patterns of regulatory mechanisms to explore their future research directions in tumor diagnosis, treatment, and prognosis. This may provide new ideas for the potential application of ncRNAs in estrogen-dependent female reproductive system tumors. |
| format | Article |
| id | doaj-art-fe9ca6710e0a4ca894792813f5dbe5fd |
| institution | Kabale University |
| issn | 1687-8337 1687-8345 |
| language | English |
| publishDate | 2021-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | International Journal of Endocrinology |
| spelling | doaj-art-fe9ca6710e0a4ca894792813f5dbe5fd2025-02-03T06:43:33ZengWileyInternational Journal of Endocrinology1687-83371687-83452021-01-01202110.1155/2021/55720635572063The Central Roles of Noncoding RNA in Estrogen-Dependent Female Reproductive System TumorsJiajie Tu0Huan Yang1Lei Jiang2Yu Chen3Yu Chen4Zhe Li5Lei Li6Yuanyuan Zhang7Xiaochun Chen8He Chen9Zhiying Yu10Key Laboratory of Anti-Inflammatory and Immune Medicine, Ministry of Education, Anhui Collaborative Innovation Center of Anti-Inflammatory and Immune Medicine, Institute of Clinical Pharmacology, Anhui Medical University, Hefei, ChinaDepartment of Gynecology, Shenzhen Second People’s Hospital, The First Affiliated Hospital of Shenzhen University Health Science Center, Shenzhen, ChinaKey Laboratory of Anti-Inflammatory and Immune Medicine, Ministry of Education, Anhui Collaborative Innovation Center of Anti-Inflammatory and Immune Medicine, Institute of Clinical Pharmacology, Anhui Medical University, Hefei, ChinaDepartment of Obstetrics and Gynecology, The First Affiliated Hospital of USTC, Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei, ChinaDepartment of Gynecology, Shenzhen Second People’s Hospital, The First Affiliated Hospital of Shenzhen University Health Science Center, Shenzhen, ChinaThe First Clinical Medical College of Southern Medical University, Guangzhou, ChinaDepartment of Gynecology, Shenzhen Second People’s Hospital, The First Affiliated Hospital of Shenzhen University Health Science Center, Shenzhen, ChinaDepartment of Gynecology, Shenzhen Second People’s Hospital, The First Affiliated Hospital of Shenzhen University Health Science Center, Shenzhen, ChinaDepartment of Gynecology, Shenzhen Second People’s Hospital, The First Affiliated Hospital of Shenzhen University Health Science Center, Shenzhen, ChinaDepartment of Gynecology, Shenzhen Second People’s Hospital, The First Affiliated Hospital of Shenzhen University Health Science Center, Shenzhen, ChinaDepartment of Gynecology, Shenzhen Second People’s Hospital, The First Affiliated Hospital of Shenzhen University Health Science Center, Shenzhen, ChinaThe pathogenesis of ovarian and endometrial cancers is closely associated with estrogen-related pathways. These estrogen-dependent tumors seriously threaten the health and quality of life in women. Noncoding RNAs (ncRNAs) are defined as RNAs that do not encode proteins, including microRNAs (miRNAs) and long noncoding RNAs (lncRNAs), both of which have been reported in estrogen-dependent female reproductive system tumors. This review systematically summarizes the role of ncRNAs in estrogen-dependent tumors and common patterns of regulatory mechanisms to explore their future research directions in tumor diagnosis, treatment, and prognosis. This may provide new ideas for the potential application of ncRNAs in estrogen-dependent female reproductive system tumors.http://dx.doi.org/10.1155/2021/5572063 |
| spellingShingle | Jiajie Tu Huan Yang Lei Jiang Yu Chen Yu Chen Zhe Li Lei Li Yuanyuan Zhang Xiaochun Chen He Chen Zhiying Yu The Central Roles of Noncoding RNA in Estrogen-Dependent Female Reproductive System Tumors International Journal of Endocrinology |
| title | The Central Roles of Noncoding RNA in Estrogen-Dependent Female Reproductive System Tumors |
| title_full | The Central Roles of Noncoding RNA in Estrogen-Dependent Female Reproductive System Tumors |
| title_fullStr | The Central Roles of Noncoding RNA in Estrogen-Dependent Female Reproductive System Tumors |
| title_full_unstemmed | The Central Roles of Noncoding RNA in Estrogen-Dependent Female Reproductive System Tumors |
| title_short | The Central Roles of Noncoding RNA in Estrogen-Dependent Female Reproductive System Tumors |
| title_sort | central roles of noncoding rna in estrogen dependent female reproductive system tumors |
| url | http://dx.doi.org/10.1155/2021/5572063 |
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