Standard: Human gastric organoids

Abstract Organoid technology provides a transformative approach to understand human physiology and pathology, offering valuable insights for scientific research and therapeutic development. Human gastric organoids, in particular, have gained significant interest for applications in disease modeling,...

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Main Authors: Fan Hong, Ronghui Tan, Ting Wang, Nanshan Zhong, Hongling Zhao, Rui-hua Xu, Lin Shen, Yingbin Liu, Xuebiao Yao, Dongxi Xiang, Lijian Hui, Jianping Xiong, Dong Gao, Bing Zhao, Zhifeng Miao, Jie Hao, Yong Li, Shijun Hu, Boqiang Fu, Guoqiang Hua, Lei Wang, Zhao-Lei Zeng, Chong Chen, Jianmin Wu, Changlin Wang, Chunnian Wang, Xianbao Zhan, Chen Song, Chunping Yu, Yingying Yang, Gengming Niu, Yalong Wang, Tongbiao Zhao, Ye-Guang Chen
Format: Article
Language:English
Published: SpringerOpen 2025-01-01
Series:Cell Regeneration
Subjects:
Online Access:https://doi.org/10.1186/s13619-024-00218-6
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author Fan Hong
Ronghui Tan
Ting Wang
Nanshan Zhong
Hongling Zhao
Rui-hua Xu
Lin Shen
Yingbin Liu
Xuebiao Yao
Dongxi Xiang
Lijian Hui
Jianping Xiong
Dong Gao
Bing Zhao
Zhifeng Miao
Jie Hao
Yong Li
Shijun Hu
Boqiang Fu
Guoqiang Hua
Lei Wang
Zhao-Lei Zeng
Chong Chen
Jianmin Wu
Changlin Wang
Chunnian Wang
Xianbao Zhan
Chen Song
Chunping Yu
Yingying Yang
Gengming Niu
Yalong Wang
Tongbiao Zhao
Ye-Guang Chen
author_facet Fan Hong
Ronghui Tan
Ting Wang
Nanshan Zhong
Hongling Zhao
Rui-hua Xu
Lin Shen
Yingbin Liu
Xuebiao Yao
Dongxi Xiang
Lijian Hui
Jianping Xiong
Dong Gao
Bing Zhao
Zhifeng Miao
Jie Hao
Yong Li
Shijun Hu
Boqiang Fu
Guoqiang Hua
Lei Wang
Zhao-Lei Zeng
Chong Chen
Jianmin Wu
Changlin Wang
Chunnian Wang
Xianbao Zhan
Chen Song
Chunping Yu
Yingying Yang
Gengming Niu
Yalong Wang
Tongbiao Zhao
Ye-Guang Chen
author_sort Fan Hong
collection DOAJ
description Abstract Organoid technology provides a transformative approach to understand human physiology and pathology, offering valuable insights for scientific research and therapeutic development. Human gastric organoids, in particular, have gained significant interest for applications in disease modeling, drug discovery, and studies of tissue regeneration and homeostasis. However, the lack of standardized quality control has limited their extensive clinical applications. The “Human Gastric Organoids” is part of a series of guidelines for human gastric organoids in China, which establishes comprehensive standards on terminology, technical specifications, testing methods, inspection rules, usage instructions, labeling, transportation, and storage, developed by experts from the Chinese Society for Cell Biology and its branch societies. Released on October 29, 2024, this guideline aims to establish standardized protocols, enhance institutional practices, and promote international standardization for clinical and research applications of human gastric organoids.
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spelling doaj-art-fe988e4a21f54fc781b6b2df955e13a12025-01-19T12:25:53ZengSpringerOpenCell Regeneration2045-97692025-01-011411910.1186/s13619-024-00218-6Standard: Human gastric organoidsFan Hong0Ronghui Tan1Ting Wang2Nanshan Zhong3Hongling Zhao4Rui-hua Xu5Lin Shen6Yingbin Liu7Xuebiao Yao8Dongxi Xiang9Lijian Hui10Jianping Xiong11Dong Gao12Bing Zhao13Zhifeng Miao14Jie Hao15Yong Li16Shijun Hu17Boqiang Fu18Guoqiang Hua19Lei Wang20Zhao-Lei Zeng21Chong Chen22Jianmin Wu23Changlin Wang24Chunnian Wang25Xianbao Zhan26Chen Song27Chunping Yu28Yingying Yang29Gengming Niu30Yalong Wang31Tongbiao Zhao32Ye-Guang Chen33Guangzhou National LaboratoryGuangzhou National LaboratoryThe State Key Laboratory of Membrane Biology, Tsinghua‑Peking Center for Life Sciences, School of Life Sciences, Tsinghua UniversityThe MOE Basic Research and Innovation Center for the Targeted Therapeutics of Solid Tumors, School of Basic Medical Sciences, Jiangxi Medical College, Nanchang UniversityBeijing Institute for Stem Cell and Regenerative MedicineState Key Laboratory of Oncology in South China, Collaborative Innovation Center for Cancer Medicine, Sun Yat-Sen University Cancer CenterState Key Laboratory of Holistic Integrative Management of Gastrointestinal Cancers, Beijing Key Laboratory of Carcinogenesis and Translational Research, Department of Gastrointestinal Oncology, Peking University Cancer Hospital and InstituteState Key Laboratory of Systems Medicine for Cancer, Shanghai Cancer Institute, Shanghai Jiaotong University School of MedicineMOE Key Laboratory of Cellular Dynamics, CAS Center for Excellence in Molecular Cell Science, University of Science and Technology of ChinaState Key Laboratory of Systems Medicine for Cancer, Shanghai Cancer Institute, Shanghai Jiaotong University School of MedicineSchool of Life Science and Technology, Shanghai Tech UniversityDepartment of Oncology, The First Affiliated Hospital of Nanchang UniversityUniversity of Chinese Academy of SciencesThe MOE Basic Research and Innovation Center for the Targeted Therapeutics of Solid Tumors, School of Basic Medical Sciences, Jiangxi Medical College, Nanchang UniversityDepartment of Surgical Oncology and General Surgery, The First Hospital of China Medical UniversityNational Stem Cell Resource Center, Institute of Zoology, Chinese Academy of SciencesDepartment of Gastrointestinal Surgery, Department of General Surgery, Guangdong Provincial People’s Hospital (Guangdong Academy of Medical Sciences), Southern Medical UniversityDepartment of Cardiovascular Surgery of the First Affiliated Hospital & Institute for Cardiovascular Science, Collaborative Innovation Center of Hematology, State Key Laboratory of Radiation Medicine and Protection, Suzhou Medical College, Soochow UniversityNational Institute of MetrologyDepartment of Radiation Oncology and Cancer Institute, Fudan University Shanghai Cancer Center Fudan UniversityBeijing Institute for Stem Cell and Regenerative MedicineState Key Laboratory of Oncology in South China, Collaborative Innovation Center for Cancer Medicine, Sun Yat-Sen University Cancer CenterGastric Cancer Center and Laboratory of Gastric Cancer, State Key Laboratory of Biotherapy, West China Hospital, Sichuan UniversityKey Laboratory of Carcinogenesis and Translational Research (Ministry of Education), Center for Cancer Bioinformatics, Peking University Cancer Hospital and InstituteChina National Institute of StandardizationDepartment of Gastrointestinal Pathology, Ningbo Diagnostic Pathology CenterDepartment of Oncology, Changhai Hospital, Second Military Medical UniversityHuayi Regeneration Technology Co., LtdLilly (China) Research and Development CenterQilu Pharmaceutical Co., LtdShang Hai OneTar Biomedicine Co., LtdGuangzhou National LaboratoryBeijing Institute for Stem Cell and Regenerative MedicineGuangzhou National LaboratoryAbstract Organoid technology provides a transformative approach to understand human physiology and pathology, offering valuable insights for scientific research and therapeutic development. Human gastric organoids, in particular, have gained significant interest for applications in disease modeling, drug discovery, and studies of tissue regeneration and homeostasis. However, the lack of standardized quality control has limited their extensive clinical applications. The “Human Gastric Organoids” is part of a series of guidelines for human gastric organoids in China, which establishes comprehensive standards on terminology, technical specifications, testing methods, inspection rules, usage instructions, labeling, transportation, and storage, developed by experts from the Chinese Society for Cell Biology and its branch societies. Released on October 29, 2024, this guideline aims to establish standardized protocols, enhance institutional practices, and promote international standardization for clinical and research applications of human gastric organoids.https://doi.org/10.1186/s13619-024-00218-6StandardHuman stomachGastric organoidsTermsDefinitionsTechnical requirements
spellingShingle Fan Hong
Ronghui Tan
Ting Wang
Nanshan Zhong
Hongling Zhao
Rui-hua Xu
Lin Shen
Yingbin Liu
Xuebiao Yao
Dongxi Xiang
Lijian Hui
Jianping Xiong
Dong Gao
Bing Zhao
Zhifeng Miao
Jie Hao
Yong Li
Shijun Hu
Boqiang Fu
Guoqiang Hua
Lei Wang
Zhao-Lei Zeng
Chong Chen
Jianmin Wu
Changlin Wang
Chunnian Wang
Xianbao Zhan
Chen Song
Chunping Yu
Yingying Yang
Gengming Niu
Yalong Wang
Tongbiao Zhao
Ye-Guang Chen
Standard: Human gastric organoids
Cell Regeneration
Standard
Human stomach
Gastric organoids
Terms
Definitions
Technical requirements
title Standard: Human gastric organoids
title_full Standard: Human gastric organoids
title_fullStr Standard: Human gastric organoids
title_full_unstemmed Standard: Human gastric organoids
title_short Standard: Human gastric organoids
title_sort standard human gastric organoids
topic Standard
Human stomach
Gastric organoids
Terms
Definitions
Technical requirements
url https://doi.org/10.1186/s13619-024-00218-6
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