In depth characterisation of the proteome of MIS-C and post COVID-19 infection in children reveals inflammatory pathway activation and evidence of tissue damage

Abstract Background Multisystem inflammatory syndrome in children (MIS-C) is a rare but severe complication that arises between two and six weeks after initial SARS-CoV-2 infection. The mechanisms underlying why only a subset of children develop this hyperinflammatory response remain unclear. Method...

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Bibliographic Details
Main Authors: Cathal Roarty, Claire Tonry, Claire McGinn, Sharon Christie, Tom Waterfield, Chris Watson
Format: Article
Language:English
Published: BMC 2025-08-01
Series:Journal of Translational Medicine
Online Access:https://doi.org/10.1186/s12967-025-06826-3
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