Obtusifolin ameliorates dry eye model in rats by reducing inflammation and blocking MAPK/NF-κB pathways

Obtusifolin ameliorates dry eye model in rats by reducing inflammation and blocking MAPK/NF-κB pathways

AIM: To investigate the functions and potential mechanisms of obtusifolin in dry eye disease (DED) in a rat model. METHODS: A rat DED model was established via topical administration of benzalkonium chloride (BAC), followed by administration of obtusifolin. Conjunctival irritation score and tear pro...

Full description

Saved in:
Bibliographic Details
Main Authors: Dan Zhu, Xiao-Yang Wu, Liang-Chang Li
Format: Article
Language:English
Published: Press of International Journal of Ophthalmology (IJO PRESS) 2025-08-01
Series:International Journal of Ophthalmology
Subjects:
dry eye disease
obtusifolin
inflammation
tear production
mitogen-activated protein kinase/nuclear factor kappa b
rats
Online Access:http://ies.ijo.cn/en_publish/2025/8/20250802.pdf
Tags: Add Tag
No Tags, Be the first to tag this record!

Internet

http://ies.ijo.cn/en_publish/2025/8/20250802.pdf

Similar Items