Two Cases of Dedifferentiated Endometrioid Carcinoma: Case Presentation and Brief Review of the Literature

Endometrioid carcinoma is the most common histological type of uterine endometrial cancer and particularly dedifferentiated endometrioid carcinomas (DEC) are less commonly observed. Silva et al. reported the biological features of UC based on the undifferentiated component of DEC, although the compo...

Full description

Saved in:
Bibliographic Details
Main Authors: Sachiko Morioka, Yasuhito Tanase, Ryuji Kawaguchi, Tomoko Uchiyama, Hiroshi Kobayash
Format: Article
Language:English
Published: Wiley 2018-01-01
Series:Case Reports in Obstetrics and Gynecology
Online Access:http://dx.doi.org/10.1155/2018/7624785
Tags: Add Tag
No Tags, Be the first to tag this record!
_version_ 1832563400910045184
author Sachiko Morioka
Yasuhito Tanase
Ryuji Kawaguchi
Tomoko Uchiyama
Hiroshi Kobayash
author_facet Sachiko Morioka
Yasuhito Tanase
Ryuji Kawaguchi
Tomoko Uchiyama
Hiroshi Kobayash
author_sort Sachiko Morioka
collection DOAJ
description Endometrioid carcinoma is the most common histological type of uterine endometrial cancer and particularly dedifferentiated endometrioid carcinomas (DEC) are less commonly observed. Silva et al. reported the biological features of UC based on the undifferentiated component of DEC, although the component represented only 20% of undifferentiated carcinoma. In this study, we report two cases of DEC with different presentation. Case 2 presented with the invasion to the bladder, rectum, and LN metastases. In contrast, the tumor in case 1 advanced into the endometrial cavity, similar to an endometrial polyp, without myometrial invasion. Hence, the diagnosis was established early. While we strive to improve the diagnosis of DEC, it is also crucial to better assess the prognosis and the appropriate treatment for the patients with established diagnosis of DEC.
format Article
id doaj-art-fe22e1a5da9f44258c73d2d3965a574c
institution Kabale University
issn 2090-6684
2090-6692
language English
publishDate 2018-01-01
publisher Wiley
record_format Article
series Case Reports in Obstetrics and Gynecology
spelling doaj-art-fe22e1a5da9f44258c73d2d3965a574c2025-02-03T01:20:26ZengWileyCase Reports in Obstetrics and Gynecology2090-66842090-66922018-01-01201810.1155/2018/76247857624785Two Cases of Dedifferentiated Endometrioid Carcinoma: Case Presentation and Brief Review of the LiteratureSachiko Morioka0Yasuhito Tanase1Ryuji Kawaguchi2Tomoko Uchiyama3Hiroshi Kobayash4Department of Obstetrics and Gynecology, Nara Medical University, Nara, JapanDepartment of Obstetrics and Gynecology, Nara Medical University, Nara, JapanDepartment of Obstetrics and Gynecology, Nara Medical University, Nara, JapanDepartment of Diagnostic Pathology, Nara Medical University, Nara, JapanDepartment of Obstetrics and Gynecology, Nara Medical University, Nara, JapanEndometrioid carcinoma is the most common histological type of uterine endometrial cancer and particularly dedifferentiated endometrioid carcinomas (DEC) are less commonly observed. Silva et al. reported the biological features of UC based on the undifferentiated component of DEC, although the component represented only 20% of undifferentiated carcinoma. In this study, we report two cases of DEC with different presentation. Case 2 presented with the invasion to the bladder, rectum, and LN metastases. In contrast, the tumor in case 1 advanced into the endometrial cavity, similar to an endometrial polyp, without myometrial invasion. Hence, the diagnosis was established early. While we strive to improve the diagnosis of DEC, it is also crucial to better assess the prognosis and the appropriate treatment for the patients with established diagnosis of DEC.http://dx.doi.org/10.1155/2018/7624785
spellingShingle Sachiko Morioka
Yasuhito Tanase
Ryuji Kawaguchi
Tomoko Uchiyama
Hiroshi Kobayash
Two Cases of Dedifferentiated Endometrioid Carcinoma: Case Presentation and Brief Review of the Literature
Case Reports in Obstetrics and Gynecology
title Two Cases of Dedifferentiated Endometrioid Carcinoma: Case Presentation and Brief Review of the Literature
title_full Two Cases of Dedifferentiated Endometrioid Carcinoma: Case Presentation and Brief Review of the Literature
title_fullStr Two Cases of Dedifferentiated Endometrioid Carcinoma: Case Presentation and Brief Review of the Literature
title_full_unstemmed Two Cases of Dedifferentiated Endometrioid Carcinoma: Case Presentation and Brief Review of the Literature
title_short Two Cases of Dedifferentiated Endometrioid Carcinoma: Case Presentation and Brief Review of the Literature
title_sort two cases of dedifferentiated endometrioid carcinoma case presentation and brief review of the literature
url http://dx.doi.org/10.1155/2018/7624785
work_keys_str_mv AT sachikomorioka twocasesofdedifferentiatedendometrioidcarcinomacasepresentationandbriefreviewoftheliterature
AT yasuhitotanase twocasesofdedifferentiatedendometrioidcarcinomacasepresentationandbriefreviewoftheliterature
AT ryujikawaguchi twocasesofdedifferentiatedendometrioidcarcinomacasepresentationandbriefreviewoftheliterature
AT tomokouchiyama twocasesofdedifferentiatedendometrioidcarcinomacasepresentationandbriefreviewoftheliterature
AT hiroshikobayash twocasesofdedifferentiatedendometrioidcarcinomacasepresentationandbriefreviewoftheliterature