Oral calcium supplementation versus placebo in mitigating citrate reactions during apheresis: an open-label randomized control trial

Oral calcium supplementation versus placebo in mitigating citrate reactions during apheresis: an open-label randomized control trial

Background: Citrate-related hypocalcemia is the most common adverse event linked with peripheral blood progenitor cell apheresis. A previous retrospective study highlighted the prophylactic effectiveness of oral calcium drinks before apheresis, supplemented with intravenous calcium gluconate. Conseq...

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Main Authors: Masaya Abe, Keiko Fujii, Nobuharu Fujii, Toshiharu Mitsuhashi, Takuya Fukumi, Yuichi Sumii, Maiko Kimura, Tomohiro Urata, Takumi Kondo, Fumio Otsuka, Yoshinobu Maeda
Format: Article
Language:English
Published: Elsevier 2024-12-01
Series:Hematology, Transfusion and Cell Therapy
Subjects:
Allogeneic peripheral blood progenitor cell collection
Citrate-related adverse effect
Oral calcium drink
Ionized calcium
Online Access:http://www.sciencedirect.com/science/article/pii/S2531137924003250
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