HPV16 E7 inhibits HBD2 expression by down-regulation of ASK1-p38 MAPK pathway in cervical cancer

HPV16 E7 inhibits HBD2 expression by down-regulation of ASK1-p38 MAPK pathway in cervical cancer

Abstract Background Recent researches indicated a down-regulation of Human beta-defensin2 (HBD2) expression in cervical cancer cells, but the mechanism and clinical significance is not clear yet. Methods In this paper, based on the data from the TCGA database, the bioinformatics analysis provided by...

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Bibliographic Details
Main Authors: Juanjuan Liao, Shanshan Deng, Bowen Shi, Meizhen Wang, Yingying Yin, Yanli Cao, Renping Liu, Xiaotian Huang, Lixia Jiang, Qiaofa Shi
Format: Article
Language:English
Published: BMC 2025-04-01
Series:Virology Journal
Subjects:
Human beta-defensin-2
Cervical cancer
HPV16
Apoptosis
Anisomycin
Online Access:https://doi.org/10.1186/s12985-025-02731-9
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