ROLE OF POLYMORPHISM FOR THE PANE1 GENE IN THE FORMATION OF REPRODUCTIVE INDICES IN PIGS
A tradeoff between reproductive success and immunity is observed in wild and laboratory animals owing to limited energy resources of an organism. Therefore, artificial selection of farm animals for reproductive indices may be accompanied by reduced immune response. Formerly, a single-nucleotide poly...
Saved in:
| Main Authors: | , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Siberian Branch of the Russian Academy of Sciences, Federal Research Center Institute of Cytology and Genetics, The Vavilov Society of Geneticists and Breeders
2015-01-01
|
| Series: | Вавиловский журнал генетики и селекции |
| Subjects: | |
| Online Access: | https://vavilov.elpub.ru/jour/article/view/247 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1832575340828950528 |
|---|---|
| author | N. S. Yudin R. B. Aitnazarov S. P. Knyazev V. A. Bekenev Yu. V. Podoba A. B. Berdibaeva M. I. Voevoda |
| author_facet | N. S. Yudin R. B. Aitnazarov S. P. Knyazev V. A. Bekenev Yu. V. Podoba A. B. Berdibaeva M. I. Voevoda |
| author_sort | N. S. Yudin |
| collection | DOAJ |
| description | A tradeoff between reproductive success and immunity is observed in wild and laboratory animals owing to limited energy resources of an organism. Therefore, artificial selection of farm animals for reproductive indices may be accompanied by reduced immune response. Formerly, a single-nucleotide polymorphism in the PANE1 gene for a minor histocompatibility antigen was demonstrated to be positively associated with immunological blood indices and negatively associated with birthweight in Landrace pigs (Huang et al., 2010). In the present study, the frequency of the SNP was determined in domestic pigs and wild boars, and its association with reproductive indices in pigs of the Large White breed. Wild boars, domestic Landrace pigs, and Large White pigs did not differ significantly in the frequency of the rare G allele of PANE1: 11,8, 12,2, and 20,0 %, respectively. Carriership of the CG genotype in females reduced the live litter size and weight. |
| format | Article |
| id | doaj-art-fdf38c96b14a4fe5aa24444e3a329883 |
| institution | Kabale University |
| issn | 2500-3259 |
| language | English |
| publishDate | 2015-01-01 |
| publisher | Siberian Branch of the Russian Academy of Sciences, Federal Research Center Institute of Cytology and Genetics, The Vavilov Society of Geneticists and Breeders |
| record_format | Article |
| series | Вавиловский журнал генетики и селекции |
| spelling | doaj-art-fdf38c96b14a4fe5aa24444e3a3298832025-02-01T09:58:00ZengSiberian Branch of the Russian Academy of Sciences, Federal Research Center Institute of Cytology and Genetics, The Vavilov Society of Geneticists and BreedersВавиловский журнал генетики и селекции2500-32592015-01-01182258262231ROLE OF POLYMORPHISM FOR THE PANE1 GENE IN THE FORMATION OF REPRODUCTIVE INDICES IN PIGSN. S. Yudin0R. B. Aitnazarov1S. P. Knyazev2V. A. Bekenev3Yu. V. Podoba4A. B. Berdibaeva5M. I. Voevoda6Institute of Cytology and Genetics SB RAS, Novosibirsk, RussiaInstitute of Cytology and Genetics SB RAS, Novosibirsk, RussiaNovosibirsk State Agrarian University, Novosibirsk, RussiaSiberian Research Institute for Animal Husbandry, Novosibirsk, RussiaInstitute of Cultivation and Genetics of Animals, Ukrainian Academy of Agrarian Sciences, Chubinskoe, Borispol region, Kiev oblast, UkraineInstitute of Biotechnology, Kyrgyz Academy of Sciences, Bishkek, Kyrgyz RepublicInstitute of Cytology and Genetics SB RAS, Novosibirsk, Russia Research Institute of Internal Medicine, Siberian Branch of the Russian Academy of Medical Sciences, Novosibirsk, RussiaA tradeoff between reproductive success and immunity is observed in wild and laboratory animals owing to limited energy resources of an organism. Therefore, artificial selection of farm animals for reproductive indices may be accompanied by reduced immune response. Formerly, a single-nucleotide polymorphism in the PANE1 gene for a minor histocompatibility antigen was demonstrated to be positively associated with immunological blood indices and negatively associated with birthweight in Landrace pigs (Huang et al., 2010). In the present study, the frequency of the SNP was determined in domestic pigs and wild boars, and its association with reproductive indices in pigs of the Large White breed. Wild boars, domestic Landrace pigs, and Large White pigs did not differ significantly in the frequency of the rare G allele of PANE1: 11,8, 12,2, and 20,0 %, respectively. Carriership of the CG genotype in females reduced the live litter size and weight.https://vavilov.elpub.ru/jour/article/view/247piglarge white breedwild hogsus scrofapane1 genesingle-nucleotide polymorphismassociationreproductive traitimmunity |
| spellingShingle | N. S. Yudin R. B. Aitnazarov S. P. Knyazev V. A. Bekenev Yu. V. Podoba A. B. Berdibaeva M. I. Voevoda ROLE OF POLYMORPHISM FOR THE PANE1 GENE IN THE FORMATION OF REPRODUCTIVE INDICES IN PIGS Вавиловский журнал генетики и селекции pig large white breed wild hog sus scrofa pane1 gene single-nucleotide polymorphism association reproductive trait immunity |
| title | ROLE OF POLYMORPHISM FOR THE PANE1 GENE IN THE FORMATION OF REPRODUCTIVE INDICES IN PIGS |
| title_full | ROLE OF POLYMORPHISM FOR THE PANE1 GENE IN THE FORMATION OF REPRODUCTIVE INDICES IN PIGS |
| title_fullStr | ROLE OF POLYMORPHISM FOR THE PANE1 GENE IN THE FORMATION OF REPRODUCTIVE INDICES IN PIGS |
| title_full_unstemmed | ROLE OF POLYMORPHISM FOR THE PANE1 GENE IN THE FORMATION OF REPRODUCTIVE INDICES IN PIGS |
| title_short | ROLE OF POLYMORPHISM FOR THE PANE1 GENE IN THE FORMATION OF REPRODUCTIVE INDICES IN PIGS |
| title_sort | role of polymorphism for the pane1 gene in the formation of reproductive indices in pigs |
| topic | pig large white breed wild hog sus scrofa pane1 gene single-nucleotide polymorphism association reproductive trait immunity |
| url | https://vavilov.elpub.ru/jour/article/view/247 |
| work_keys_str_mv | AT nsyudin roleofpolymorphismforthepane1geneintheformationofreproductiveindicesinpigs AT rbaitnazarov roleofpolymorphismforthepane1geneintheformationofreproductiveindicesinpigs AT spknyazev roleofpolymorphismforthepane1geneintheformationofreproductiveindicesinpigs AT vabekenev roleofpolymorphismforthepane1geneintheformationofreproductiveindicesinpigs AT yuvpodoba roleofpolymorphismforthepane1geneintheformationofreproductiveindicesinpigs AT abberdibaeva roleofpolymorphismforthepane1geneintheformationofreproductiveindicesinpigs AT mivoevoda roleofpolymorphismforthepane1geneintheformationofreproductiveindicesinpigs |