Enhanced variant neutralization through glycan masking of SARS-CoV-2 XBB1.5 RBD

Enhanced variant neutralization through glycan masking of SARS-CoV-2 XBB1.5 RBD

SARS-CoV-2 continues to evolve antigenically under the immune pressure exerted by both natural infection and vaccination. As new variants emerge, we face the recurring challenge of updating vaccines at significant financial cost to maintain their efficacy. To address this, novel strategies are neede...

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Bibliographic Details
Main Authors: Joey Olivier, Charlotte George, Chloe Qingzhou Huang, Sneha B. Sujit, Paul Tonks, Diego Cantoni, Joe Grove, Laura O’Reilly, Johannes Geiger, Christian Dohmen, Verena Mummert, Anne Rosalind Samuel, Christian Plank, Rebecca Kinsley, Nigel Temperton, Martina Pfranger, Ralf Wagner, Jonathan L. Heeney, Sneha Vishwanath, George W. Carnell
Format: Article
Language:English
Published: Taylor & Francis Group 2025-12-01
Series:Emerging Microbes and Infections
Subjects:
Glycan masking
neutralising antibodies
next generation vaccines
SARS-CoV-2
receptor binding domain
Online Access:https://www.tandfonline.com/doi/10.1080/22221751.2025.2502011
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https://www.tandfonline.com/doi/10.1080/22221751.2025.2502011

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