A 54-Year-Old Woman with Donor Cell Origin of Multiple Myeloma after Allogeneic Hematopoietic Stem Cell Transplantation for the Treatment of CML
Chronic myeloid leukemia is a myeloproliferative disorder that may be treated with hematopoietic stem cell transplantation (HSCT). While posttransplantation relapse of disease resulting from a failure to eradicate the patient’s original leukemia could occur, patients may also rarely develop a second...
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Format: | Article |
Language: | English |
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Wiley
2016-01-01
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Series: | Case Reports in Hematology |
Online Access: | http://dx.doi.org/10.1155/2016/6751914 |
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author | Erika Maestas Shikha Jain Patrick Stiff |
author_facet | Erika Maestas Shikha Jain Patrick Stiff |
author_sort | Erika Maestas |
collection | DOAJ |
description | Chronic myeloid leukemia is a myeloproliferative disorder that may be treated with hematopoietic stem cell transplantation (HSCT). While posttransplantation relapse of disease resulting from a failure to eradicate the patient’s original leukemia could occur, patients may also rarely develop a secondary malignancy or myelodysplastic syndrome (MDS) of donor origin termed donor cell leukemia (DCL). Cases of donor-derived acute myeloid leukemia (AML) or MDS after HSCT or solid tumor transplantation have been published. However, very few cases of donor-derived multiple myeloma (MM) exist. We describe a patient who developed a donor-derived MM following allogeneic HSCT from a sibling donor. |
format | Article |
id | doaj-art-fdd55d2f5e164837a4a84b086a20a1d2 |
institution | Kabale University |
issn | 2090-6560 2090-6579 |
language | English |
publishDate | 2016-01-01 |
publisher | Wiley |
record_format | Article |
series | Case Reports in Hematology |
spelling | doaj-art-fdd55d2f5e164837a4a84b086a20a1d22025-02-03T00:59:48ZengWileyCase Reports in Hematology2090-65602090-65792016-01-01201610.1155/2016/67519146751914A 54-Year-Old Woman with Donor Cell Origin of Multiple Myeloma after Allogeneic Hematopoietic Stem Cell Transplantation for the Treatment of CMLErika Maestas0Shikha Jain1Patrick Stiff2Loyola University Medical Center, 2160 South First Avenue, Maywood, IL 60153, USALoyola University Medical Center, 2160 South First Avenue, Maywood, IL 60153, USALoyola University Medical Center, 2160 South First Avenue, Maywood, IL 60153, USAChronic myeloid leukemia is a myeloproliferative disorder that may be treated with hematopoietic stem cell transplantation (HSCT). While posttransplantation relapse of disease resulting from a failure to eradicate the patient’s original leukemia could occur, patients may also rarely develop a secondary malignancy or myelodysplastic syndrome (MDS) of donor origin termed donor cell leukemia (DCL). Cases of donor-derived acute myeloid leukemia (AML) or MDS after HSCT or solid tumor transplantation have been published. However, very few cases of donor-derived multiple myeloma (MM) exist. We describe a patient who developed a donor-derived MM following allogeneic HSCT from a sibling donor.http://dx.doi.org/10.1155/2016/6751914 |
spellingShingle | Erika Maestas Shikha Jain Patrick Stiff A 54-Year-Old Woman with Donor Cell Origin of Multiple Myeloma after Allogeneic Hematopoietic Stem Cell Transplantation for the Treatment of CML Case Reports in Hematology |
title | A 54-Year-Old Woman with Donor Cell Origin of Multiple Myeloma after Allogeneic Hematopoietic Stem Cell Transplantation for the Treatment of CML |
title_full | A 54-Year-Old Woman with Donor Cell Origin of Multiple Myeloma after Allogeneic Hematopoietic Stem Cell Transplantation for the Treatment of CML |
title_fullStr | A 54-Year-Old Woman with Donor Cell Origin of Multiple Myeloma after Allogeneic Hematopoietic Stem Cell Transplantation for the Treatment of CML |
title_full_unstemmed | A 54-Year-Old Woman with Donor Cell Origin of Multiple Myeloma after Allogeneic Hematopoietic Stem Cell Transplantation for the Treatment of CML |
title_short | A 54-Year-Old Woman with Donor Cell Origin of Multiple Myeloma after Allogeneic Hematopoietic Stem Cell Transplantation for the Treatment of CML |
title_sort | 54 year old woman with donor cell origin of multiple myeloma after allogeneic hematopoietic stem cell transplantation for the treatment of cml |
url | http://dx.doi.org/10.1155/2016/6751914 |
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