Gut-derived Faecalibaculum rodentium exerts anti-cancer effects on colorectal cancer by modulating PDPN-CLEC-2 signaling pathway

Gut-derived Faecalibaculum rodentium exerts anti-cancer effects on colorectal cancer by modulating PDPN-CLEC-2 signaling pathway

ABSTRACT Dynamic changes in microbial composition are related to the progression of colorectal cancer (CRC); however, specific microbes with anti-CRC properties have not been identified. Here, we aimed to determine the effect of Faecalibaculum rodentium on CRC progression. In this study, the effect...

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Bibliographic Details
Main Authors: Xiaojuan Yang, Miao Liu, Ting Wang, Xinjuan Ma, Zhirong Guan, Bin Ma, Xiangguo Duan, Chunxia Su
Format: Article
Language:English
Published: American Society for Microbiology 2025-08-01
Series:mSystems
Subjects:
acetate
colorectal cancer
CD8+T-cell immunity
CLEC-2
Faecalibaculum rodentium
PDPN
Online Access:https://journals.asm.org/doi/10.1128/msystems.00148-25
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