Bilateral Asynchronous Renal Cell Carcinoma with Metastatic Involvement of the Tongue

Renal cell carcinoma (RCC) has a propensity for distant organ metastasis and late recurrence, involving not only the ipsilateral but also contralateral kidney. Lingual metastasis by RCC is rare. We present an unusual case of bilateral asynchronous RCC. Involvement of the right kidney was discovered...

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Main Authors: Naseem Ghazali, Charlotte Davis, A. W. Barrett, John V. Tighe
Format: Article
Language:English
Published: Wiley 2012-01-01
Series:Case Reports in Pathology
Online Access:http://dx.doi.org/10.1155/2012/729642
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author Naseem Ghazali
Charlotte Davis
A. W. Barrett
John V. Tighe
author_facet Naseem Ghazali
Charlotte Davis
A. W. Barrett
John V. Tighe
author_sort Naseem Ghazali
collection DOAJ
description Renal cell carcinoma (RCC) has a propensity for distant organ metastasis and late recurrence, involving not only the ipsilateral but also contralateral kidney. Lingual metastasis by RCC is rare. We present an unusual case of bilateral asynchronous RCC. Involvement of the right kidney was discovered only after a metastatic tongue lesion was diagnosed. The original RCC had been treated by left nephrectomy 14 years previously. Due to end-stage primary pulmonary malignancy, and poor function of the remaining kidney, immunotherapy was unsuitable. Palliative local resection of the lingual metastasis alleviated functional difficulties and was preventative against airway obstruction, but the patient died five months later.
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spelling doaj-art-fd316e29fca842cfbfd9e91d17a69dd72025-02-03T01:27:46ZengWileyCase Reports in Pathology2090-67812090-679X2012-01-01201210.1155/2012/729642729642Bilateral Asynchronous Renal Cell Carcinoma with Metastatic Involvement of the TongueNaseem Ghazali0Charlotte Davis1A. W. Barrett2John V. Tighe3Maxillofacial Unit, Queen Victoria Hospital NHS Foundation Trust, Holtye Road, East Grinstead RH19 3DZ, UKMaxillofacial Unit, Queen Victoria Hospital NHS Foundation Trust, Holtye Road, East Grinstead RH19 3DZ, UKDepartment of Histopathology, Queen Victoria Hospital NHS Foundation Trust, Holtye Road, East Grinstead RH19 3DZ, UKMaxillofacial Unit, Queen Victoria Hospital NHS Foundation Trust, Holtye Road, East Grinstead RH19 3DZ, UKRenal cell carcinoma (RCC) has a propensity for distant organ metastasis and late recurrence, involving not only the ipsilateral but also contralateral kidney. Lingual metastasis by RCC is rare. We present an unusual case of bilateral asynchronous RCC. Involvement of the right kidney was discovered only after a metastatic tongue lesion was diagnosed. The original RCC had been treated by left nephrectomy 14 years previously. Due to end-stage primary pulmonary malignancy, and poor function of the remaining kidney, immunotherapy was unsuitable. Palliative local resection of the lingual metastasis alleviated functional difficulties and was preventative against airway obstruction, but the patient died five months later.http://dx.doi.org/10.1155/2012/729642
spellingShingle Naseem Ghazali
Charlotte Davis
A. W. Barrett
John V. Tighe
Bilateral Asynchronous Renal Cell Carcinoma with Metastatic Involvement of the Tongue
Case Reports in Pathology
title Bilateral Asynchronous Renal Cell Carcinoma with Metastatic Involvement of the Tongue
title_full Bilateral Asynchronous Renal Cell Carcinoma with Metastatic Involvement of the Tongue
title_fullStr Bilateral Asynchronous Renal Cell Carcinoma with Metastatic Involvement of the Tongue
title_full_unstemmed Bilateral Asynchronous Renal Cell Carcinoma with Metastatic Involvement of the Tongue
title_short Bilateral Asynchronous Renal Cell Carcinoma with Metastatic Involvement of the Tongue
title_sort bilateral asynchronous renal cell carcinoma with metastatic involvement of the tongue
url http://dx.doi.org/10.1155/2012/729642
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