The immunological bases of alemtuzumab as induction-therapy in pediatric-onset multiple sclerosis

Pediatric-Onset Multiple Sclerosis (POMS) is characterized by both white and grey matter inflammation, as well as by a higher risk of long-term physical and cognitive disability. The peculiar immunopathogenic mechanisms of POMS suggests that the use of induction therapies, including alemtuzumab (ALT...

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Bibliographic Details
Main Authors: Marco Puthenparampil, Marta Gaggiola, Francesca Rinaldi, M. Nosadini, S. Sartori, Paola Perini, Paolo Gallo
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-01-01
Series:Frontiers in Immunology
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Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2024.1509987/full
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