Endothelial cell Piezo1 promotes vascular smooth muscle cell differentiation on large arteries

Endothelial cell Piezo1 promotes vascular smooth muscle cell differentiation on large arteries

Vascular stabilization is a mechanosensitive process, in part driven by blood flow. Here, we demonstrate the involvement of the mechanosensitive ion channel, Piezo1, in promoting arterial accumulation of vascular smooth muscle cells (vSMCs) during zebrafish development. Using a series of small molec...

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Bibliographic Details
Main Authors: Javier Abello, Ying Yin, Yonghui Zhao, Josh Maurer, Jihui Lee, Cherokee Bodell, Jahmiera Richee, Abigail J. Clevenger, Zarek Burton, Megan E. Goeckel, Michelle Lin, Stephanie Grainger, Carmen M. Halabi, Shreya A. Raghavan, Rajan Sah, Amber N. Stratman
Format: Article
Language:English
Published: Elsevier 2025-03-01
Series:European Journal of Cell Biology
Subjects:
Vascular smooth muscle
Mural cell
Zebrafish
Piezo1
Arterial stabilization
Online Access:http://www.sciencedirect.com/science/article/pii/S0171933524000906
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