Effectiveness and safety of direct oral anticoagulants versus vitamin K antagonists in atrial fibrillation patients with liver disease: a systematic review and meta-analysis

Effectiveness and safety of direct oral anticoagulants versus vitamin K antagonists in atrial fibrillation patients with liver disease: a systematic review and meta-analysis

IntroductionPatients with atrial fibrillation (AF) and liver disease, particularly cirrhosis, are frequently excluded from anticoagulation trials, leaving the optimal therapeutic strategy uncertain.MethodsThis study aimed to compare the effectiveness and safety of direct oral anticoagulants (DOACs)...

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Bibliographic Details
Main Authors:	Qiang Zhou, Xiang Liu, Shuyu Liu, Zhichun Gu, Yanzi Wu, Yuansu Yang, Yingying Tao, Meng Wei
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2025-07-01
Series:	Frontiers in Pharmacology
Subjects:	atrial fibrillation liver disease direct oral anticoagulants vitamin K antagonists anticoagulants meta-analysis
Online Access:	https://www.frontiersin.org/articles/10.3389/fphar.2025.1620394/full
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