Transcriptomic profile of microglia following inflammation-sensitized hypoxic-ischemic brain injury in neonatal rats suggests strong contribution to neutrophil chemotaxis and activation

Abstract Background Inflammation-sensitized hypoxic-ischemic brain injury significantly contributes to neonatal mortality as affected neonates do not benefit from standard cooling treatments. To get further insight into inflammatory responses involved, we experimentally investigated the immune respo...

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Bibliographic Details
Main Authors: Anna-Sophie Bremer, Nico Henschel, Hannah Burkard, Maria Eugenia Bernis, Thomas Ulas, Hemmen Sabir
Format: Article
Language:English
Published: BMC 2025-07-01
Series:Journal of Neuroinflammation
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Online Access:https://doi.org/10.1186/s12974-025-03516-1
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