Targeting the mTOR-Autophagy Axis: Unveiling Therapeutic Potentials in Osteoporosis

Targeting the mTOR-Autophagy Axis: Unveiling Therapeutic Potentials in Osteoporosis

Osteoporosis (OP) is a widespread age-related disorder marked by decreased bone density and increased fracture risk, presenting a significant public health challenge. Central to the development and progression of OP is the dysregulation of the mechanistic target of the rapamycin (mTOR)-signaling pat...

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Bibliographic Details
Main Authors: Rongjin Chen, Chenhui Yang, Fei Yang, Ao Yang, Hefang Xiao, Bo Peng, Changshun Chen, Bin Geng, Yayi Xia
Format: Article
Language:English
Published: MDPI AG 2024-11-01
Series:Biomolecules
Subjects:
osteoporosis
mTOR signaling pathway
autophagy
bone metabolism
therapeutic targeting
Online Access:https://www.mdpi.com/2218-273X/14/11/1452
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