RNA-seq analysis reveals key genes associated with downregulation of APE1 in esophageal squamous cell carcinoma

RNA-seq analysis reveals key genes associated with downregulation of APE1 in esophageal squamous cell carcinoma

ObjectiveThis study aims to explore the impact of APE1 gene knockout on the transcriptome of esophageal cancer cells and conduct a preliminary screening of APE1-regulated target genes to provide a basis for understanding APE1 target genes and finding new anti-esophageal cancer therapeutic targets.Me...

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Bibliographic Details
Main Authors: Alan Chu, Xiao Liu, Shijia Liu, Mengxi Li, Rui Song, Lanlan Gan, Yongtai Wang, Zongwen Liu, Chen Sun
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-04-01
Series:Frontiers in Genetics
Subjects:
RNA-seq
Ape1
esophageal cancer
molecular target
bioinformatics
Online Access:https://www.frontiersin.org/articles/10.3389/fgene.2025.1549371/full
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